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1. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

2. Potassium depletion is LEAST likely to occur in a patient using
A.
B.
C.
D.
E.

3. During ovulation, peak plasma concentration(s) of which of the following hormone(s) will be reached?
I. luteinizing hormone (LH)
II. follicle-stimulating hormone (FSH)
III. progesterone
A.
B.
C.
D.
E.

4. Which of the following is (are) true of isotretinoin (Accutane)?
I. in pregnancy category X
II. indicated for the treatment of psoriasis
III. useful for treatment of alopecia
A.
B.
C.
D.
E.

5. A common adverse effect associated with the chronic use of magnesium antacids is
A.
B.
C.
D.
E.

6. Which of the following drugs is (are) classified as a selective serotonin reuptake inhibitor (SSRI)?
I. citalopram (Celexa)
II. sertraline (Zoloft)
III. venlafaxine (Effexor)
A.
B.
C.
D.
E.

7. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

8. Which of the following is (are) true of iso-tretinoin (Accutane)?
A.
B.
C.
D.
E.

9. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action to
A.
B.
C.
D.
E.

10. Simvastatin (Zocor) acts by
A.
B.
C.
D.
E.

11. Stavudine (Zerit) is an antiviral agent employed in the treatment of
A.
B.
C.
D.
E.

12. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

13. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

14. The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate?
I. methenamine mandelate
II. acetazolamide
III. sodium bicarbonate
A.
B.
C.
D.
E.

15. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

16. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by
A.
B.
C.
D.
E.

17. Which of the following is (are) classified as aminopenicillins?
I. bacampicillin
II. amoxicillin
III. ampicillin
A.
B.
C.
D.
E.

18. Torsemide (Demadex) is most similar in action to
A.
B.
C.
D.
E.

19. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

20. Clonidine may best be described as a (an)
A.
B.
C.
D.
E.

21. Which of the products listed below are vaccines?
I. Sandimmune
II. Prograf
III. LYMErix
A.
B.
C.
D.
E.

22. Which of the following calcium channel blockers may be employed parenterally in the treatment of cardiac arrhythmias?
I. verapamil (Isoptin, Calan)
II. isradipine (DynaCirc)
III. amlodipine (Norvasc)
A.
B.
C.
D.
E.

23. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

24. Which of the following drugs may interfere with ethanol metabolism?
I. metronidazole (Flagyl)
II. chlorpropamide (Diabinese)
III. disulfiram (Antabuse)
A.
B.
C.
D.
E.

25. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

26. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of
A.
B.
C.
D.
E.

27. A disadvantage in the use of cimetidine (Tagamet) is its ability to cause
A.
B.
C.
D.
E.

28. Which of the following agents decreases the production of hydrochloric acid in the stomach?
I. olsalazine
II. calcium carbonate
III. lansoprazole
A.
B.
C.
D.
E.

29. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

30. Amrinone (Inocor) is a drug that produces
A.
B.
C.
D.
E.

31. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

32. Which of the following agents is (are) indicated for the treatment of convulsive disorders
I. clonidine
II. tiagabine
III. topiramate
A.
B.
C.
D.
E.

33. Colestipol HCl (Colestid) can best be classified as a (an)
A.
B.
C.
D.
E.

34. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

35. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

36. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

37. Reflex tachycardia is an adverse effect most likely to be associated with the use of which of the following drugs?
A.
B.
C.
D.
E.

38. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

39. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)?
I. may be administered by inhalation
II. may be administered parenterally
III. used to treat RSV infections
A.
B.
C.
D.
E.

40. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac)?
A.
B.
C.
D.
E.

41. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

42. Which of the following antimicrobial products is (are) prodrugs?
I. cefpodoxime proxetil
II. dirithromycin
III. clindamycin
A.
B.
C.
D.
E.

43. Which of the following agents are classified as macrolides?
I. amikacin
II. polymyxin B
III. azithromycin
A.
B.
C.
D.
E.

44. Which of the following agents is (are) classified as a leukotriene receptor antagonist?
I. ipratropium bromide
II. zileuton
III. montelukast sodium
A.
B.
C.
D.
E.

45. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

46. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

47. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

48. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

49. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

50. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

51. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

52. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.

53. Patients who are sensitive to aspirin should avoid the use of
I. codeine
II. oxaprozin
III. ibuprofen
A.
B.
C.
D.
E.

54. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

55. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug?
I. administered orally
II. stimulates erythrocyte production
III. produced by recombinant DNA technology
A.
B.
C.
D.
E.

56. Cromolyn sodium (Intal, Nasalcrom, Opticrom) is a drug that is
A.
B.
C.
D.
E.

57. The dose of liothyronine sodium that is approximately equivalent to 100 ).!g of levothyroxine sodium (Synthroid) USP is
A.
B.
C.
D.
E.

58. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

59. Latanoprost (Xalatan) can best be described as a (an)
A.
B.
C.
D.
E.

60. Gingival hyperplasia, hirsutism, and ataxia are adverse effects associated with the use of
A.
B.
C.
D.
E.