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1. Which one of the following is NOT a progestin?
A.
B.
C.
D.
E.

2. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

3. Simvastatin (Zocor) acts by
A.
B.
C.
D.
E.

4. Didanosine (Videx) can best be described as a (an)
A.
B.
C.
D.
E.

5. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

6. Which of the products listed below are vaccines?
I. Sandimmune
II. Prograf
III. LYMErix
A.
B.
C.
D.
E.

7. Which of the following is a COMT inhibitor?
A.
B.
C.
D.
E.

8. Patients who are sensitive to aspirin should avoid the use of
I. codeine
II. oxaprozin
III. ibuprofen
A.
B.
C.
D.
E.

9. The thiazide derivative diazoxide (Hyperstat)
A.
B.
C.
D.
E.

10. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

11. Benzoyl peroxide is commonly employed in the treatment of
A.
B.
C.
D.
E.

12. Lactulose (Cephulac, Chronulac)
I. is a laxative
II. decreases blood ammonia levels
III. is an artificial sweetener
A.
B.
C.
D.
E.

13. Torsemide (Demadex) is most similar in action to
A.
B.
C.
D.
E.

14. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

15. In monitoring a patient receiving warfarin for the treatment of acute myocardial infarction, it is important to maintain the INR between
A.
B.
C.
D.
E.

16. Which one of the following antibiotics is a third-generation cephalosporin?
A.
B.
C.
D.
E.

17. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

18. Which of the following beta-adrenergic blocking agents also exhibit alpha1-adrenergic blocking action?
I. timolol (Blocadren)
II. sotalol (Betapace)
III. labetalol (Normodyne, Trandate)
A.
B.
C.
D.
E.

19. Nicardipine (Cardene) is indicated for the treatment of
I. angina pectoris
II. hypertension
III. ventricular tachycardia
A.
B.
C.
D.
E.

20. The anti-inflammatory effect of NSAIDs is due to their ability to
1. inhibit prostaglandin synthesis
II. inhibit the stimulation of the chemoreceptor trigger zone (CTZ)
III. reset the hypothalamic "setpoint"
A.
B.
C.
D.
E.

21. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

22. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

23. Amrinone (Inocor) is most similar in action to
A.
B.
C.
D.
E.

24. Latanoprost (Xalatan) can best be described as a (an)
A.
B.
C.
D.
E.

25. Which of the following morphine derivatives is most likely to cause dependence?
A.
B.
C.
D.
E.

26. Reflex tachycardia is an adverse effect most likely to be associated with the use of which of the following drugs?
A.
B.
C.
D.
E.

27. Reduced clotting ability of the blood is associated with the administration of
I. clopidogrel (Plavix)
II. abciximab (ReoPro)
III. filgrastim (Neupogen)
A.
B.
C.
D.
E.

28. Minoxidil is an antihypertensive agent that works by
A.
B.
C.
D.
E.

29. Which of the following is true of permethrin (Nix, Elimite)?
I. It is only used topically.
II. It is used to treat topical fungal infections.
III. It is used to enhance permeation of drugs through the skin.
A.
B.
C.
D.
E.

30. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

31. Which of the following agents is NOT likely to reduce blood sugar in a patient with type II diabetes mellitus?
I. glucagon
II. pioglitazone
III. repaglinide
A.
B.
C.
D.
E.

32. Amrinone (Inocor) is a drug that produces
A.
B.
C.
D.
E.

33. Which of the following is a gold compound?
I. aurothioglucose (Solganal)
II. goserelin acetate (Zoladex)
III. ergonovine
A.
B.
C.
D.
E.

34. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac)?
A.
B.
C.
D.
E.

35. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action to
A.
B.
C.
D.
E.

36. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

37. Which of the following agents is (are) indicated for use in the treatment of emesis?
I. dronabinol (Marinol)
II. granisetron (Kytril)
III. nalbumetone (Relafen)
A.
B.
C.
D.
E.

38. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?
A.
B.
C.
D.
E.

39. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

40. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

41. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?
A.
B.
C.
D.
E.

42. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

43. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

44. Olsalazine sodium (Dipentum) is employed in the treatment of
A.
B.
C.
D.
E.

45. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

46. Which of the following is (are) true of iso-tretinoin (Accutane)?
A.
B.
C.
D.
E.

47. Which of the following agents decreases the production of hydrochloric acid in the stomach?
I. olsalazine
II. calcium carbonate
III. lansoprazole
A.
B.
C.
D.
E.

48. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

49. Colestipol HCl (Colestid) can best be classified as a (an)
A.
B.
C.
D.
E.

50. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.

51. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

52. Iron is required by the body to maintain normal
A.
B.
C.
D.
E.

53. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

54. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

55. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

56. Which of the following is (are) true of alteplase (Activase)?
A.
B.
C.
D.
E.

57. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

58. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

59. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

60. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.