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1. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

2. Nicardipine (Cardene) is indicated for the treatment of
I. angina pectoris
II. hypertension
III. ventricular tachycardia
A.
B.
C.
D.
E.

3. The thiazide derivative diazoxide (Hyperstat)
A.
B.
C.
D.
E.

4. Which of the following is (are) dopaminergic antiparkinson agents?
I. ropinirole (Requip)
II. pergolide (Permax)
III. procyclidine (Kemadrin)
A.
B.
C.
D.
E.

5. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)
A.
B.
C.
D.
E.

6. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

7. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

8. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

9. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

10. Which of the following is (are) true of sal-meterol (Serevent)?
I. for the treatment of acute asthma attacks
II. available in an aerosol and inhalation powder form
III. beta 2 agonist
A.
B.
C.
D.
E.

11. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

12. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac)?
A.
B.
C.
D.
E.

13. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

14. Auranofin (Ridaura) is employed in the treatment of
A.
B.
C.
D.
E.

15. Which of the following agents is (are) indicated for the treatment of convulsive disorders
I. clonidine
II. tiagabine
III. topiramate
A.
B.
C.
D.
E.

16. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

17. Which of the following is (are) classified as aminopenicillins?
I. bacampicillin
II. amoxicillin
III. ampicillin
A.
B.
C.
D.
E.

18. Which of the following is (are) true of milrinone lactate (Primacor)?
I. may be administered orally or parenterally
II. produces a positive inotropic action
III. produces vasodilation
A.
B.
C.
D.
E.

19. Which of the following is (are) true of isotretinoin (Accutane)?
I. in pregnancy category X
II. indicated for the treatment of psoriasis
III. useful for treatment of alopecia
A.
B.
C.
D.
E.

20. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

21. Which of the following drugs is (are) sulfonamides?
A.
B.
C.
D.
E.

22. Which of the products listed below are vaccines?
I. Sandimmune
II. Prograf
III. LYMErix
A.
B.
C.
D.
E.

23. During ovulation, peak plasma concentration(s) of which of the following hormone(s) will be reached?
I. luteinizing hormone (LH)
II. follicle-stimulating hormone (FSH)
III. progesterone
A.
B.
C.
D.
E.

24. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

25. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

26. Which of the following is an active metabolite of primidone (Mysoline)?
I. acetylcholine
II. phenylethylmalonamide
III. phenobarbital
A.
B.
C.
D.
E.

27. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

28. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

29. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

30. A drug that decreases the formation of uric acid is
A.
B.
C.
D.
E.

31. Cromolyn sodium (Intal, Nasalcrom, Opticrom) is a drug that is
A.
B.
C.
D.
E.

32. Drugs employed in reducing elevated serum cholesterol include(s)
I. gemfibrozil (Lopid)
II. cerivastatin (Baycol)
III. pioglitazone (Aetos)
A.
B.
C.
D.
E.

33. Which of the following drugs may interfere with ethanol metabolism?
I. metronidazole (Flagyl)
II. chlorpropamide (Diabinese)
III. disulfiram (Antabuse)
A.
B.
C.
D.
E.

34. A common adverse effect associated with the chronic use of magnesium antacids is
A.
B.
C.
D.
E.

35. Which of the following hormones is released from the posterior pituitary gland?
I. growth hormone
II. follicle-stimulating hormone (FSH)
III. oxytocin
A.
B.
C.
D.
E.

36. Which of the following is (are) true of fentanyl?
I. available as a transdermal system
II. used as a local anesthetic
III. may be used as a cough suppressant
A.
B.
C.
D.
E.

37. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

38. Simvastatin (Zocor) acts by
A.
B.
C.
D.
E.

39. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

40. Zafirlukast (Accolate) is a drug that can best be classified as a (an)
A.
B.
C.
D.
E.

41. Which one of the following barbiturates is likely to be the shortest acting?
A.
B.
C.
D.
E.

42. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?
A.
B.
C.
D.
E.

43. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

44. Which of the following drugs is (are) H1-histamine receptor antagonists?
I. diphenhydramine
II. hydroxyzine
III. famotidine
A.
B.
C.
D.
E.

45. Which of the following beta-adrenergic blocking agents also exhibit alpha1-adrenergic blocking action?
I. timolol (Blocadren)
II. sotalol (Betapace)
III. labetalol (Normodyne, Trandate)
A.
B.
C.
D.
E.

46. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

47. Prolonged activity (8 to 10 hours) is an advantage in the use of which of the following topical decongestants?
I. phenylephrine
II. oxymetazoline
III. xylometazoline
A.
B.
C.
D.
E.

48. The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate?
I. methenamine mandelate
II. acetazolamide
III. sodium bicarbonate
A.
B.
C.
D.
E.

49. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

50. The primary site of action of triamterene (Dyrenium) and spironolactone (Aldactone) is the
A.
B.
C.
D.
E.

51. Lactulose (Cephulac, Chronulac)
I. is a laxative
II. decreases blood ammonia levels
III. is an artificial sweetener
A.
B.
C.
D.
E.

52. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)?
I. may be administered by inhalation
II. may be administered parenterally
III. used to treat RSV infections
A.
B.
C.
D.
E.

53. Thiazide diuretics decrease the excretion of
A.
B.
C.
D.
E.

54. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action to
A.
B.
C.
D.
E.

55. Which of the following agents are classified as macrolides?
I. amikacin
II. polymyxin B
III. azithromycin
A.
B.
C.
D.
E.

56. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

57. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.

58. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

59. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

60. Alteplase (Activase) is employed clinically as a (an)
A.
B.
C.
D.
E.