Page 1 of 3

1. Diflunisal (Dolobid) is most likely to be prescribed for the treatment of
A.
B.
C.
D.
E.

2. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

3. Which one of the following barbiturates is likely to be the shortest acting?
A.
B.
C.
D.
E.

4. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

5. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

6. The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate?
I. methenamine mandelate
II. acetazolamide
III. sodium bicarbonate
A.
B.
C.
D.
E.

7. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.
A.
B.
C.
D.
E.

8. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

9. Clonidine may best be described as a (an)
A.
B.
C.
D.
E.

10. Which of the following is (are) true of finasteride (Proscar, Propecia)?
I. pregnancy category X
II. employed in the treatment of BPH
III. used in alopecia treatment
A.
B.
C.
D.
E.

11. Beta carotene is considered to be a precursor for
A.
B.
C.
D.
E.

12. Tamoxifen (Nolvadex) can best be characterized as a (an)
A.
B.
C.
D.
E.

13. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

14. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

15. Which of the following statements is (are) true of potassium?
I. It is a divalent cation.
II. It facilitates the utilization of glucose by cells.
III. It is the principal intracellular ion.
A.
B.
C.
D.
E.

16. Which of the following is (are) employed as an antifungal agent?
I. cycloserine
II. mafenide
III. terbinafine
A.
B.
C.
D.
E.

17. Phosphate binding is likely to occur when which of the following antacids are administered?
I. aluminum hydroxide
II. sodium bicarbonate
III. calcium carbonate
A.
B.
C.
D.
E.

18. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

19. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.

20. Which of the products listed below are vaccines?
I. Sandimmune
II. Prograf
III. LYMErix
A.
B.
C.
D.
E.

21. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

22. Which of the following is true of permethrin (Nix, Elimite)?
I. It is only used topically.
II. It is used to treat topical fungal infections.
III. It is used to enhance permeation of drugs through the skin.
A.
B.
C.
D.
E.

23. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

24. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

25. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

26. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

27. Danazol (Danocrine) can best be classified as a (an)
A.
B.
C.
D.
E.

28. Which of the following is (are) true of fentanyl?
I. available as a transdermal system
II. used as a local anesthetic
III. may be used as a cough suppressant
A.
B.
C.
D.
E.

29. Which of the following antiarrhythmic agents is (are) associated with an adverse effect known as cinchonism?
A.
B.
C.
D.
E.

30. Which of the following hormones is released from the posterior pituitary gland?
I. growth hormone
II. follicle-stimulating hormone (FSH)
III. oxytocin
A.
B.
C.
D.
E.

31. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

32. Potassium depletion is LEAST likely to occur in a patient using
A.
B.
C.
D.
E.

33. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

34. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

35. Propylthiouracil is used for the same therapeutic indication as
A.
B.
C.
D.
E.

36. Drugs employed in reducing elevated serum cholesterol include(s)
I. gemfibrozil (Lopid)
II. cerivastatin (Baycol)
III. pioglitazone (Aetos)
A.
B.
C.
D.
E.

37. Which of the following is an active metabolite of primidone (Mysoline)?
I. acetylcholine
II. phenylethylmalonamide
III. phenobarbital
A.
B.
C.
D.
E.

38. Most antipsychotic drugs can be said to have which of the following actions?
A.
B.
C.
D.
E.

39. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

40. Lactulose (Cephulac, Chronulac)
I. is a laxative
II. decreases blood ammonia levels
III. is an artificial sweetener
A.
B.
C.
D.
E.

41. An agent that would be most likely to cause drug-induced bronchospasm is
A.
B.
C.
D.
E.

42. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

43. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

44. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

45. The dose of liothyronine sodium that is approximately equivalent to 100 ).!g of levothyroxine sodium (Synthroid) USP is
A.
B.
C.
D.
E.

46. A uricosuric drug is one that
A.
B.
C.
D.
E.

47. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

48. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

49. Isotretinoin (Accutane) is a drug employed in the treatment of severe recalcitrant cystic acne. Which one of the following is NOT an adverse effect associated with its use?
A.
B.
C.
D.
E.

50. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

51. Which of the following is a gold compound?
I. aurothioglucose (Solganal)
II. goserelin acetate (Zoladex)
III. ergonovine
A.
B.
C.
D.
E.

52. Latanoprost (Xalatan) can best be described as a (an)
A.
B.
C.
D.
E.

53. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

54. Simvastatin (Zocor) acts by
A.
B.
C.
D.
E.

55. Which of the following agents are classified as macrolides?
I. amikacin
II. polymyxin B
III. azithromycin
A.
B.
C.
D.
E.

56. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

57. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

58. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

59. Which of the following calcium channel blockers may be employed parenterally in the treatment of cardiac arrhythmias?
I. verapamil (Isoptin, Calan)
II. isradipine (DynaCirc)
III. amlodipine (Norvasc)
A.
B.
C.
D.
E.

60. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.