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1. Which of the following is (are) classified as a broad-spectrum antifungal agent?
I. fluorouracil
II. mebendazole
III. miconazole
A.
B.
C.
D.
E.

2. Stavudine (Zerit) is an antiviral agent employed in the treatment of
A.
B.
C.
D.
E.

3. Most antipsychotic drugs can be said to have which of the following actions?
A.
B.
C.
D.
E.

4. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

5. Pamidronate sodium (Aredia) is indicated for the treatment of
A.
B.
C.
D.
E.

6. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

7. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

8. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

9. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

10. Which of the following antimicrobial products is (are) prodrugs?
I. cefpodoxime proxetil
II. dirithromycin
III. clindamycin
A.
B.
C.
D.
E.

11. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?
A.
B.
C.
D.
E.

12. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

13. Patients receiving amiodarone (Cordarone) should be monitored for the development of
A.
B.
C.
D.
E.

14. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

15. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

16. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action to
A.
B.
C.
D.
E.

17. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

18. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

19. Selegeline (Eldepryl) can best be described as a (an)
A.
B.
C.
D.
E.

20. Which of the following agents is (are) classified as antiseptics or germicides?
I. chlorhexidine gluconate (Hibiclens)
II. glutaraldehyde (Cidex)
III. benzalkonium chloride (Zephiran)
A.
B.
C.
D.
E.

21. Lactulose (Cephulac, Chronulac)
I. is a laxative
II. decreases blood ammonia levels
III. is an artificial sweetener
A.
B.
C.
D.
E.

22. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

23. Which of the following drugs are available in a transdermal form for the prevention of motion sickness?
A.
B.
C.
D.
E.

24. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug?
I. administered orally
II. stimulates erythrocyte production
III. produced by recombinant DNA technology
A.
B.
C.
D.
E.

25. Beta carotene is considered to be a precursor for
A.
B.
C.
D.
E.

26. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

27. Timentin is a product that contains ticarcillin disodium and clavulanate potassium. Clavulanate potassium
A.
B.
C.
D.
E.

28. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.
A.
B.
C.
D.
E.

29. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

30. Clonidine may best be described as a (an)
A.
B.
C.
D.
E.

31. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

32. Which of the following is an active metabolite of primidone (Mysoline)?
I. acetylcholine
II. phenylethylmalonamide
III. phenobarbital
A.
B.
C.
D.
E.

33. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

34. Finasteride (Proscar, Propecia) can best be described as a (an)
A.
B.
C.
D.
E.

35. Drugs employed in reducing elevated serum cholesterol include(s)
I. gemfibrozil (Lopid)
II. cerivastatin (Baycol)
III. pioglitazone (Aetos)
A.
B.
C.
D.
E.

36. Which of the following agents is (are) indicated for the treatment of convulsive disorders
I. clonidine
II. tiagabine
III. topiramate
A.
B.
C.
D.
E.

37. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

38. Which of the following statements is (are) TRUE of buprenorphine (Buprenex)?
I. It is a narcotic agonist-antagonist drug.
II. It is only administered parenterally.
III. It is a phenothiazine derivative.
A.
B.
C.
D.
E.

39. Diflunisal (Dolobid) is most likely to be prescribed for the treatment of
A.
B.
C.
D.
E.

40. Which one of the following beta-adrenergic blocking agents has the greatest lipid solubility?
A.
B.
C.
D.
E.

41. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

42. Which one of the following agents can be administered with ampicillin and other penicillins to achieve higher blood levels of the penicillin?
A.
B.
C.
D.
E.

43. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

44. Auranofin (Ridaura) is employed in the treatment of
A.
B.
C.
D.
E.

45. Which of the following is true of permethrin (Nix, Elimite)?
I. It is only used topically.
II. It is used to treat topical fungal infections.
III. It is used to enhance permeation of drugs through the skin.
A.
B.
C.
D.
E.

46. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

47. Which of the following is (are) true of milrinone lactate (Primacor)?
I. may be administered orally or parenterally
II. produces a positive inotropic action
III. produces vasodilation
A.
B.
C.
D.
E.

48. Zafirlukast (Accolate) is a drug that can best be classified as a (an)
A.
B.
C.
D.
E.

49. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

50. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

51. Olsalazine sodium (Dipentum) is employed in the treatment of
A.
B.
C.
D.
E.

52. Which one of the following antibiotics is a third-generation cephalosporin?
A.
B.
C.
D.
E.

53. Which of the following drugs is (are) classified as a selective serotonin reuptake inhibitor (SSRI)?
I. citalopram (Celexa)
II. sertraline (Zoloft)
III. venlafaxine (Effexor)
A.
B.
C.
D.
E.

54. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

55. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

56. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

57. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

58. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

59. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.

60. Which of the following is (are) true of isotretinoin (Accutane)?
I. in pregnancy category X
II. indicated for the treatment of psoriasis
III. useful for treatment of alopecia
A.
B.
C.
D.
E.