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1. Phosphate binding is likely to occur when which of the following antacids are administered?
I. aluminum hydroxide
II. sodium bicarbonate
III. calcium carbonate
A.
B.
C.
D.
E.

2. Danazol (Danocrine) can best be classified as a (an)
A.
B.
C.
D.
E.

3. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

4. Olsalazine sodium (Dipentum) is employed in the treatment of
A.
B.
C.
D.
E.

5. Vidarabine (Vira-A) is an antiviral agent indicated for the treatment of
A.
B.
C.
D.
E.

6. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterol
A.
B.
C.
D.
E.

7. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

8. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

9. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

10. Cyclophosphamide (Cytoxan) is an example of a (an)
A.
B.
C.
D.
E.

11. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

12. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

13. Isotretinoin (Accutane) is a drug employed in the treatment of severe recalcitrant cystic acne. Which one of the following is NOT an adverse effect associated with its use?
A.
B.
C.
D.
E.

14. Drugs employed in reducing elevated serum cholesterol include(s)
I. gemfibrozil (Lopid)
II. cerivastatin (Baycol)
III. pioglitazone (Aetos)
A.
B.
C.
D.
E.

15. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

16. Which of the following agents have cortical stimulant action?
I. buspirone
II. pemoline
III. methamphetamine
A.
B.
C.
D.
E.

17. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

18. Zidovudine (Retrovir) is indicated for the treatment of patients with
I. hepatitis B infection
II. herpes simplex infections
III. human immunodeficiency virus (HIV) infection
A.
B.
C.
D.
E.

19. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

20. Thiazide diuretics decrease the excretion of
A.
B.
C.
D.
E.

21. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

22. Which of the following is (are) true of fentanyl?
I. available as a transdermal system
II. used as a local anesthetic
III. may be used as a cough suppressant
A.
B.
C.
D.
E.

23. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

24. Which of the following is true of pilocarpine (Isopto Carpine, Pilostat)?
I. similar pharmacologic action to dorzolamide (Trusopt)
II. direct-acting mydriatic
III. ingredient in Ocusert ocular therapeutic system
A.
B.
C.
D.
E.

25. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac)?
A.
B.
C.
D.
E.

26. A disadvantage in the use of cimetidine (Tagamet) is its ability to cause
A.
B.
C.
D.
E.

27. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

28. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.

29. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.

30. Most antipsychotic drugs can be said to have which of the following actions?
A.
B.
C.
D.
E.

31. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

32. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

33. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

34. Which one of the following beta-adrenergic blocking agents has the greatest lipid solubility?
A.
B.
C.
D.
E.

35. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

36. Which of the following agents is (are) indicated for the treatment of chronic inflammatory bowel disease?
A.
B.
C.
D.
E.

37. Tamoxifen (Nolvadex) can best be characterized as a (an)
A.
B.
C.
D.
E.

38. In monitoring a patient receiving warfarin for the treatment of acute myocardial infarction, it is important to maintain the INR between
A.
B.
C.
D.
E.

39. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

40. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

41. Which of the following hormones is released from the posterior pituitary gland?
I. growth hormone
II. follicle-stimulating hormone (FSH)
III. oxytocin
A.
B.
C.
D.
E.

42. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

43. Selegeline (Eldepryl) can best be described as a (an)
A.
B.
C.
D.
E.

44. Alteplase (Activase) is employed clinically as a (an)
A.
B.
C.
D.
E.

45. Which of the following agents is (are) classified as antiseptics or germicides?
I. chlorhexidine gluconate (Hibiclens)
II. glutaraldehyde (Cidex)
III. benzalkonium chloride (Zephiran)
A.
B.
C.
D.
E.

46. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

47. The primary site of action of triamterene (Dyrenium) and spironolactone (Aldactone) is the
A.
B.
C.
D.
E.

48. Which of the following drugs is (are) sulfonamides?
A.
B.
C.
D.
E.

49. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

50. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

51. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

52. Colestipol HCl (Colestid) can best be classified as a (an)
A.
B.
C.
D.
E.

53. The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate?
I. methenamine mandelate
II. acetazolamide
III. sodium bicarbonate
A.
B.
C.
D.
E.

54. Reflex tachycardia is an adverse effect most likely to be associated with the use of which of the following drugs?
A.
B.
C.
D.
E.

55. The thiazide derivative diazoxide (Hyperstat)
A.
B.
C.
D.
E.

56. Which of the following statements is (are) TRUE of buprenorphine (Buprenex)?
I. It is a narcotic agonist-antagonist drug.
II. It is only administered parenterally.
III. It is a phenothiazine derivative.
A.
B.
C.
D.
E.

57. Which of the following is true of finasteride (Propecia, Proscar)?
I. useful in treating BPH
II. used to treat some types of alopecia
III. a corticosteroid
A.
B.
C.
D.
E.

58. Which of the following antiarrhythmic agents is (are) associated with an adverse effect known as cinchonism?
A.
B.
C.
D.
E.

59. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

60. Benzoyl peroxide is commonly employed in the treatment of
A.
B.
C.
D.
E.