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1. Endorphins are
A.
B.
C.
D.
E.

2. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

3. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

4. Patients receiving amiodarone (Cordarone) should be monitored for the development of
A.
B.
C.
D.
E.

5. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

6. An agent that would be most likely to cause drug-induced bronchospasm is
A.
B.
C.
D.
E.

7. Nicardipine (Cardene) is indicated for the treatment of
I. angina pectoris
II. hypertension
III. ventricular tachycardia
A.
B.
C.
D.
E.

8. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

9. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

10. Minoxidil is an antihypertensive agent that works by
A.
B.
C.
D.
E.

11. Which of the following antimicrobial products is (are) prodrugs?
I. cefpodoxime proxetil
II. dirithromycin
III. clindamycin
A.
B.
C.
D.
E.

12. Which of the following is (are) true of dobut amine (Dobutrex)?
I. antidepressant
II. only administered parenterally
III. beta! agonist
A.
B.
C.
D.
E.

13. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

14. Which of the following drugs is (are) sulfonamides?
A.
B.
C.
D.
E.

15. Gingival hyperplasia, hirsutism, and ataxia are adverse effects associated with the use of
A.
B.
C.
D.
E.

16. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

17. Which of the following is (are) true of sim-vastatin (Zocor)?
I. HMG-CoA reductase inhibitor
II. pregnancy category X
III. antiviral
A.
B.
C.
D.
E.

18. Which of the following drugs are available in a transdermal form for the prevention of motion sickness?
A.
B.
C.
D.
E.

19. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

20. Which of the following is (are) true of iso-tretinoin (Accutane)?
A.
B.
C.
D.
E.

21. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

22. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

23. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.
A.
B.
C.
D.
E.

24. Which of the following is (are) employed as an antifungal agent?
I. cycloserine
II. mafenide
III. terbinafine
A.
B.
C.
D.
E.

25. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

26. Olsalazine sodium (Dipentum) is employed in the treatment of
A.
B.
C.
D.
E.

27. Which of the following hormones is released from the posterior pituitary gland?
I. growth hormone
II. follicle-stimulating hormone (FSH)
III. oxytocin
A.
B.
C.
D.
E.

28. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

29. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

30. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

31. Which of the following agents is (are) indicated for the treatment of chronic inflammatory bowel disease?
A.
B.
C.
D.
E.

32. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)
A.
B.
C.
D.
E.

33. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

34. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

35. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action to
A.
B.
C.
D.
E.

36. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

37. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?
A.
B.
C.
D.
E.

38. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

39. After oral administration, the greatest amount of iron absorption occurs in the
A.
B.
C.
D.
E.

40. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

41. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

42. Isotretinoin (Accutane) is a drug employed in the treatment of severe recalcitrant cystic acne. Which one of the following is NOT an adverse effect associated with its use?
A.
B.
C.
D.
E.

43. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

44. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.

45. Lactulose (Cephulac, Chronulac)
I. is a laxative
II. decreases blood ammonia levels
III. is an artificial sweetener
A.
B.
C.
D.
E.

46. Which of the following is (are) true of milrinone lactate (Primacor)?
I. may be administered orally or parenterally
II. produces a positive inotropic action
III. produces vasodilation
A.
B.
C.
D.
E.

47. A disadvantage in the use of cimetidine (Tagamet) is its ability to cause
A.
B.
C.
D.
E.

48. Which of the following is (are) classified as aminopenicillins?
I. bacampicillin
II. amoxicillin
III. ampicillin
A.
B.
C.
D.
E.

49. Cyclophosphamide (Cytoxan) is an example of a (an)
A.
B.
C.
D.
E.

50. Which of the following agents have cortical stimulant action?
I. buspirone
II. pemoline
III. methamphetamine
A.
B.
C.
D.
E.

51. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

52. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

53. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

54. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterol
A.
B.
C.
D.
E.

55. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

56. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

57. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by
A.
B.
C.
D.
E.

58. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

59. Which of the following bronchodilators act by inhibiting phosphodiesterase?
I. dyphylline (Lufyllin)
II. salmeterol (Serevent)
III. nedocromil sodium (Tilade)
A.
B.
C.
D.
E.

60. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.