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1. Which of the following calcium channel blockers may be employed parenterally in the treatment of cardiac arrhythmias?
I. verapamil (Isoptin, Calan)
II. isradipine (DynaCirc)
III. amlodipine (Norvasc)
A.
B.
C.
D.
E.

2. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

3. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

4. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

5. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

6. Patients receiving amiodarone (Cordarone) should be monitored for the development of
A.
B.
C.
D.
E.

7. Phosphate binding is likely to occur when which of the following antacids are administered?
I. aluminum hydroxide
II. sodium bicarbonate
III. calcium carbonate
A.
B.
C.
D.
E.

8. Which of the following drugs is (are) H1-histamine receptor antagonists?
I. diphenhydramine
II. hydroxyzine
III. famotidine
A.
B.
C.
D.
E.

9. Which of the following agents is (are) classified as antiseptics or germicides?
I. chlorhexidine gluconate (Hibiclens)
II. glutaraldehyde (Cidex)
III. benzalkonium chloride (Zephiran)
A.
B.
C.
D.
E.

10. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

11. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

12. Effects expected as a result of inhaling the smoke of cannabis (marijuana) include
I. decreased pulse rate
II. perceptual changes
III. vascular congestion of the eye
A.
B.
C.
D.
E.

13. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

14. In monitoring a patient receiving warfarin for the treatment of acute myocardial infarction, it is important to maintain the INR between
A.
B.
C.
D.
E.

15. Which of the following is (are) true of dobut amine (Dobutrex)?
I. antidepressant
II. only administered parenterally
III. beta! agonist
A.
B.
C.
D.
E.

16. Which of the following bronchodilators act by inhibiting phosphodiesterase?
I. dyphylline (Lufyllin)
II. salmeterol (Serevent)
III. nedocromil sodium (Tilade)
A.
B.
C.
D.
E.

17. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.

18. Alteplase (Activase) is employed clinically as a (an)
A.
B.
C.
D.
E.

19. Propylthiouracil is used for the same therapeutic indication as
A.
B.
C.
D.
E.

20. Which of the following is (are) dopaminergic antiparkinson agents?
I. ropinirole (Requip)
II. pergolide (Permax)
III. procyclidine (Kemadrin)
A.
B.
C.
D.
E.

21. Vidarabine (Vira-A) is an antiviral agent indicated for the treatment of
A.
B.
C.
D.
E.

22. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

23. Which of the following is a gold compound?
I. aurothioglucose (Solganal)
II. goserelin acetate (Zoladex)
III. ergonovine
A.
B.
C.
D.
E.

24. Which one of the following antimicrobial agents would be MOST useful in the treatment of an infection caused by beta-Iactamase-producing staphylococci?
A.
B.
C.
D.
E.

25. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

26. Reflex tachycardia is an adverse effect most likely to be associated with the use of which of the following drugs?
A.
B.
C.
D.
E.

27. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

28. Which of the products listed below are vaccines?
I. Sandimmune
II. Prograf
III. LYMErix
A.
B.
C.
D.
E.

29. Which of the following is (are) true of sim-vastatin (Zocor)?
I. HMG-CoA reductase inhibitor
II. pregnancy category X
III. antiviral
A.
B.
C.
D.
E.

30. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

31. Amrinone (Inocor) is a drug that produces
A.
B.
C.
D.
E.

32. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

33. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by
A.
B.
C.
D.
E.

34. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

35. Amrinone (Inocor) is most similar in action to
A.
B.
C.
D.
E.

36. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

37. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterol
A.
B.
C.
D.
E.

38. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

39. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

40. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

41. Iron is required by the body to maintain normal
A.
B.
C.
D.
E.

42. Which of the following is (are) true of sal-meterol (Serevent)?
I. for the treatment of acute asthma attacks
II. available in an aerosol and inhalation powder form
III. beta 2 agonist
A.
B.
C.
D.
E.

43. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

44. Clonidine may best be described as a (an)
A.
B.
C.
D.
E.

45. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.
A.
B.
C.
D.
E.

46. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

47. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

48. The anti-inflammatory effect of NSAIDs is due to their ability to
1. inhibit prostaglandin synthesis
II. inhibit the stimulation of the chemoreceptor trigger zone (CTZ)
III. reset the hypothalamic "setpoint"
A.
B.
C.
D.
E.

49. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)
A.
B.
C.
D.
E.

50. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

51. Which of the following is an active metabolite of primidone (Mysoline)?
I. acetylcholine
II. phenylethylmalonamide
III. phenobarbital
A.
B.
C.
D.
E.

52. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug?
I. administered orally
II. stimulates erythrocyte production
III. produced by recombinant DNA technology
A.
B.
C.
D.
E.

53. Zidovudine (Retrovir) is indicated for the treatment of patients with
I. hepatitis B infection
II. herpes simplex infections
III. human immunodeficiency virus (HIV) infection
A.
B.
C.
D.
E.

54. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

55. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

56. Isotretinoin (Accutane) is a drug employed in the treatment of severe recalcitrant cystic acne. Which one of the following is NOT an adverse effect associated with its use?
A.
B.
C.
D.
E.

57. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

58. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

59. Which of the following agents is (are) indicated for use in the treatment of emesis?
I. dronabinol (Marinol)
II. granisetron (Kytril)
III. nalbumetone (Relafen)
A.
B.
C.
D.
E.

60. Torsemide (Demadex) is most similar in action to
A.
B.
C.
D.
E.