Page 1 of 3

1. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

2. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

3. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

4. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?
A.
B.
C.
D.
E.

5. Which of the following drugs are available in a transdermal form for the prevention of motion sickness?
A.
B.
C.
D.
E.

6. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

7. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

8. Which one of the following antimicrobial agents would be MOST useful in the treatment of an infection caused by beta-Iactamase-producing staphylococci?
A.
B.
C.
D.
E.

9. During ovulation, peak plasma concentration(s) of which of the following hormone(s) will be reached?
I. luteinizing hormone (LH)
II. follicle-stimulating hormone (FSH)
III. progesterone
A.
B.
C.
D.
E.

10. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

11. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

12. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

13. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

14. Diflunisal (Dolobid) is most likely to be prescribed for the treatment of
A.
B.
C.
D.
E.

15. Which of the following is true of finasteride (Propecia, Proscar)?
I. useful in treating BPH
II. used to treat some types of alopecia
III. a corticosteroid
A.
B.
C.
D.
E.

16. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac)?
A.
B.
C.
D.
E.

17. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

18. Which of the following is true of permethrin (Nix, Elimite)?
I. It is only used topically.
II. It is used to treat topical fungal infections.
III. It is used to enhance permeation of drugs through the skin.
A.
B.
C.
D.
E.

19. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

20. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)?
I. may be administered by inhalation
II. may be administered parenterally
III. used to treat RSV infections
A.
B.
C.
D.
E.

21. Which of the following is (are) true of isotretinoin (Accutane)?
I. in pregnancy category X
II. indicated for the treatment of psoriasis
III. useful for treatment of alopecia
A.
B.
C.
D.
E.

22. Finasteride (Proscar, Propecia) can best be described as a (an)
A.
B.
C.
D.
E.

23. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

24. Gingival hyperplasia, hirsutism, and ataxia are adverse effects associated with the use of
A.
B.
C.
D.
E.

25. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterol
A.
B.
C.
D.
E.

26. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

27. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

28. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

29. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

30. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

31. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by
A.
B.
C.
D.
E.

32. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.

33. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)
A.
B.
C.
D.
E.

34. Didanosine (Videx) can best be described as a (an)
A.
B.
C.
D.
E.

35. Which one of the following agents can be administered with ampicillin and other penicillins to achieve higher blood levels of the penicillin?
A.
B.
C.
D.
E.

36. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

37. Clonidine may best be described as a (an)
A.
B.
C.
D.
E.

38. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

39. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

40. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

41. Which of the following agents is (are) classified as a leukotriene receptor antagonist?
I. ipratropium bromide
II. zileuton
III. montelukast sodium
A.
B.
C.
D.
E.

42. Lactulose (Cephulac, Chronulac)
I. is a laxative
II. decreases blood ammonia levels
III. is an artificial sweetener
A.
B.
C.
D.
E.

43. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

44. Iron is required by the body to maintain normal
A.
B.
C.
D.
E.

45. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.

46. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

47. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

48. Which one of the following antihistamines would be LEAST likely to cause sedation?
A.
B.
C.
D.
E.

49. Which of the following beta-adrenergic blocking agents also exhibit alpha1-adrenergic blocking action?
I. timolol (Blocadren)
II. sotalol (Betapace)
III. labetalol (Normodyne, Trandate)
A.
B.
C.
D.
E.

50. Amrinone (Inocor) is most similar in action to
A.
B.
C.
D.
E.

51. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

52. Which of the following is (are) classified as a broad-spectrum antifungal agent?
I. fluorouracil
II. mebendazole
III. miconazole
A.
B.
C.
D.
E.

53. The primary site of action of triamterene (Dyrenium) and spironolactone (Aldactone) is the
A.
B.
C.
D.
E.

54. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

55. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

56. Beta carotene is considered to be a precursor for
A.
B.
C.
D.
E.

57. Which of the following agents are classified as macrolides?
I. amikacin
II. polymyxin B
III. azithromycin
A.
B.
C.
D.
E.

58. Patients who are sensitive to aspirin should avoid the use of
I. codeine
II. oxaprozin
III. ibuprofen
A.
B.
C.
D.
E.

59. Which of the following agents is (are) indicated for use in the treatment of emesis?
I. dronabinol (Marinol)
II. granisetron (Kytril)
III. nalbumetone (Relafen)
A.
B.
C.
D.
E.

60. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.