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1. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

2. A uricosuric drug is one that
A.
B.
C.
D.
E.

3. Didanosine (Videx) can best be described as a (an)
A.
B.
C.
D.
E.

4. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

5. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

6. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

7. Which of the following is an active metabolite of primidone (Mysoline)?
I. acetylcholine
II. phenylethylmalonamide
III. phenobarbital
A.
B.
C.
D.
E.

8. Timentin is a product that contains ticarcillin disodium and clavulanate potassium. Clavulanate potassium
A.
B.
C.
D.
E.

9. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

10. Prolonged activity (8 to 10 hours) is an advantage in the use of which of the following topical decongestants?
I. phenylephrine
II. oxymetazoline
III. xylometazoline
A.
B.
C.
D.
E.

11. Which of the following cancer chemotherapeutic agents is (are) classified as an antimetabolite?
I. mercaptopurine (Purinethol)
II. fluorouracil (Adrucil)
III. cytarabine (Cytosar-U)
A.
B.
C.
D.
E.

12. Which of the following is a COMT inhibitor?
A.
B.
C.
D.
E.

13. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterol
A.
B.
C.
D.
E.

14. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

15. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

16. An agent that would be most likely to cause drug-induced bronchospasm is
A.
B.
C.
D.
E.

17. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)
A.
B.
C.
D.
E.

18. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

19. Potassium depletion is LEAST likely to occur in a patient using
A.
B.
C.
D.
E.

20. In monitoring a patient receiving warfarin for the treatment of acute myocardial infarction, it is important to maintain the INR between
A.
B.
C.
D.
E.

21. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

22. Patients who are sensitive to aspirin should avoid the use of
I. codeine
II. oxaprozin
III. ibuprofen
A.
B.
C.
D.
E.

23. The dose of liothyronine sodium that is approximately equivalent to 100 ).!g of levothyroxine sodium (Synthroid) USP is
A.
B.
C.
D.
E.

24. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

25. Finasteride (Proscar, Propecia) can best be described as a (an)
A.
B.
C.
D.
E.

26. Which one of the following agents can be administered with ampicillin and other penicillins to achieve higher blood levels of the penicillin?
A.
B.
C.
D.
E.

27. Minoxidil is an antihypertensive agent that works by
A.
B.
C.
D.
E.

28. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

29. Beta carotene is considered to be a precursor for
A.
B.
C.
D.
E.

30. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

31. Diflunisal (Dolobid) is most likely to be prescribed for the treatment of
A.
B.
C.
D.
E.

32. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

33. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

34. Which of the following is (are) classified as a broad-spectrum antifungal agent?
I. fluorouracil
II. mebendazole
III. miconazole
A.
B.
C.
D.
E.

35. Cromolyn sodium (Intal, Nasalcrom, Opticrom) is a drug that is
A.
B.
C.
D.
E.

36. Which of the following drugs is (are) classified as a selective serotonin reuptake inhibitor (SSRI)?
I. citalopram (Celexa)
II. sertraline (Zoloft)
III. venlafaxine (Effexor)
A.
B.
C.
D.
E.

37. Which of the following statements is (are) true of potassium?
I. It is a divalent cation.
II. It facilitates the utilization of glucose by cells.
III. It is the principal intracellular ion.
A.
B.
C.
D.
E.

38. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

39. Phosphate binding is likely to occur when which of the following antacids are administered?
I. aluminum hydroxide
II. sodium bicarbonate
III. calcium carbonate
A.
B.
C.
D.
E.

40. Which of the following is (are) employed as an antifungal agent?
I. cycloserine
II. mafenide
III. terbinafine
A.
B.
C.
D.
E.

41. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

42. Tamoxifen (Nolvadex) can best be characterized as a (an)
A.
B.
C.
D.
E.

43. Which of the following is true of finasteride (Propecia, Proscar)?
I. useful in treating BPH
II. used to treat some types of alopecia
III. a corticosteroid
A.
B.
C.
D.
E.

44. Alteplase (Activase) is employed clinically as a (an)
A.
B.
C.
D.
E.

45. A common adverse effect associated with the chronic use of magnesium antacids is
A.
B.
C.
D.
E.

46. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

47. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

48. Which of the following calcium channel blockers may be employed parenterally in the treatment of cardiac arrhythmias?
I. verapamil (Isoptin, Calan)
II. isradipine (DynaCirc)
III. amlodipine (Norvasc)
A.
B.
C.
D.
E.

49. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

50. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug?
I. administered orally
II. stimulates erythrocyte production
III. produced by recombinant DNA technology
A.
B.
C.
D.
E.

51. Colestipol HCl (Colestid) can best be classified as a (an)
A.
B.
C.
D.
E.

52. A disadvantage in the use of cimetidine (Tagamet) is its ability to cause
A.
B.
C.
D.
E.

53. Effects expected as a result of inhaling the smoke of cannabis (marijuana) include
I. decreased pulse rate
II. perceptual changes
III. vascular congestion of the eye
A.
B.
C.
D.
E.

54. Thiazide diuretics decrease the excretion of
A.
B.
C.
D.
E.

55. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of
A.
B.
C.
D.
E.

56. Which of the following morphine derivatives is most likely to cause dependence?
A.
B.
C.
D.
E.

57. Which of the following agents is (are) indicated for the treatment of convulsive disorders
I. clonidine
II. tiagabine
III. topiramate
A.
B.
C.
D.
E.

58. Which one of the following barbiturates is likely to be the shortest acting?
A.
B.
C.
D.
E.

59. Stavudine (Zerit) is an antiviral agent employed in the treatment of
A.
B.
C.
D.
E.

60. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.