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1. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

2. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

3. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by
A.
B.
C.
D.
E.

4. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

5. The anti-inflammatory effect of NSAIDs is due to their ability to
1. inhibit prostaglandin synthesis
II. inhibit the stimulation of the chemoreceptor trigger zone (CTZ)
III. reset the hypothalamic "setpoint"
A.
B.
C.
D.
E.

6. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

7. Which of the following bronchodilators act by inhibiting phosphodiesterase?
I. dyphylline (Lufyllin)
II. salmeterol (Serevent)
III. nedocromil sodium (Tilade)
A.
B.
C.
D.
E.

8. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

9. Drugs employed in reducing elevated serum cholesterol include(s)
I. gemfibrozil (Lopid)
II. cerivastatin (Baycol)
III. pioglitazone (Aetos)
A.
B.
C.
D.
E.

10. Which of the following is (are) true of finasteride (Proscar, Propecia)?
I. pregnancy category X
II. employed in the treatment of BPH
III. used in alopecia treatment
A.
B.
C.
D.
E.

11. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

12. Which of the following agents is (are) indicated for the treatment of chronic inflammatory bowel disease?
A.
B.
C.
D.
E.

13. Most antipsychotic drugs can be said to have which of the following actions?
A.
B.
C.
D.
E.

14. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

15. Which of the following hormones is released from the posterior pituitary gland?
I. growth hormone
II. follicle-stimulating hormone (FSH)
III. oxytocin
A.
B.
C.
D.
E.

16. Which of the following is true of permethrin (Nix, Elimite)?
I. It is only used topically.
II. It is used to treat topical fungal infections.
III. It is used to enhance permeation of drugs through the skin.
A.
B.
C.
D.
E.

17. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

18. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

19. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterol
A.
B.
C.
D.
E.

20. Which of the following is true of finasteride (Propecia, Proscar)?
I. useful in treating BPH
II. used to treat some types of alopecia
III. a corticosteroid
A.
B.
C.
D.
E.

21. The thiazide derivative diazoxide (Hyperstat)
A.
B.
C.
D.
E.

22. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

23. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

24. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

25. Stavudine (Zerit) is an antiviral agent employed in the treatment of
A.
B.
C.
D.
E.

26. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)?
I. may be administered by inhalation
II. may be administered parenterally
III. used to treat RSV infections
A.
B.
C.
D.
E.

27. Cromolyn sodium (Intal, Nasalcrom, Opticrom) is a drug that is
A.
B.
C.
D.
E.

28. Which of the following calcium channel blockers may be employed parenterally in the treatment of cardiac arrhythmias?
I. verapamil (Isoptin, Calan)
II. isradipine (DynaCirc)
III. amlodipine (Norvasc)
A.
B.
C.
D.
E.

29. Which of the following agents is (are) indicated for use in the treatment of emesis?
I. dronabinol (Marinol)
II. granisetron (Kytril)
III. nalbumetone (Relafen)
A.
B.
C.
D.
E.

30. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.
A.
B.
C.
D.
E.

31. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

32. Which of the following drugs may interfere with ethanol metabolism?
I. metronidazole (Flagyl)
II. chlorpropamide (Diabinese)
III. disulfiram (Antabuse)
A.
B.
C.
D.
E.

33. Which of the following is a gold compound?
I. aurothioglucose (Solganal)
II. goserelin acetate (Zoladex)
III. ergonovine
A.
B.
C.
D.
E.

34. Timentin is a product that contains ticarcillin disodium and clavulanate potassium. Clavulanate potassium
A.
B.
C.
D.
E.

35. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

36. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

37. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

38. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

39. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

40. Zafirlukast (Accolate) is a drug that can best be classified as a (an)
A.
B.
C.
D.
E.

41. A uricosuric drug is one that
A.
B.
C.
D.
E.

42. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac)?
A.
B.
C.
D.
E.

43. Cyclophosphamide (Cytoxan) is an example of a (an)
A.
B.
C.
D.
E.

44. Thiazide diuretics decrease the excretion of
A.
B.
C.
D.
E.

45. Amrinone (Inocor) is most similar in action to
A.
B.
C.
D.
E.

46. Which of the following is (are) true of alteplase (Activase)?
A.
B.
C.
D.
E.

47. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

48. An agent that would be most likely to cause drug-induced bronchospasm is
A.
B.
C.
D.
E.

49. A drug that decreases the formation of uric acid is
A.
B.
C.
D.
E.

50. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

51. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

52. Which one of the following beta-adrenergic blocking agents has the greatest lipid solubility?
A.
B.
C.
D.
E.

53. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

54. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

55. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

56. Which of the following beta-adrenergic blocking agents also exhibit alpha1-adrenergic blocking action?
I. timolol (Blocadren)
II. sotalol (Betapace)
III. labetalol (Normodyne, Trandate)
A.
B.
C.
D.
E.

57. Simvastatin (Zocor) acts by
A.
B.
C.
D.
E.

58. After oral administration, the greatest amount of iron absorption occurs in the
A.
B.
C.
D.
E.

59. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

60. Which of the following is (are) classified as a broad-spectrum antifungal agent?
I. fluorouracil
II. mebendazole
III. miconazole
A.
B.
C.
D.
E.