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1. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

2. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.

3. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.
A.
B.
C.
D.
E.

4. Nicardipine (Cardene) is indicated for the treatment of
I. angina pectoris
II. hypertension
III. ventricular tachycardia
A.
B.
C.
D.
E.

5. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

6. Which of the following is (are) true of alteplase (Activase)?
A.
B.
C.
D.
E.

7. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

8. Finasteride (Proscar, Propecia) can best be described as a (an)
A.
B.
C.
D.
E.

9. Which of the following is (are) true of finasteride (Proscar, Propecia)?
I. pregnancy category X
II. employed in the treatment of BPH
III. used in alopecia treatment
A.
B.
C.
D.
E.

10. Which one of the following antihistamines would be LEAST likely to cause sedation?
A.
B.
C.
D.
E.

11. Which of the following is (are) classified as aminopenicillins?
I. bacampicillin
II. amoxicillin
III. ampicillin
A.
B.
C.
D.
E.

12. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

13. Which of the following statements is (are) TRUE of buprenorphine (Buprenex)?
I. It is a narcotic agonist-antagonist drug.
II. It is only administered parenterally.
III. It is a phenothiazine derivative.
A.
B.
C.
D.
E.

14. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

15. A uricosuric drug is one that
A.
B.
C.
D.
E.

16. A disadvantage in the use of cimetidine (Tagamet) is its ability to cause
A.
B.
C.
D.
E.

17. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

18. Which of the following is (are) employed as an antifungal agent?
I. cycloserine
II. mafenide
III. terbinafine
A.
B.
C.
D.
E.

19. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

20. Simvastatin (Zocor) acts by
A.
B.
C.
D.
E.

21. Which of the following agents is (are) indicated for the treatment of chronic inflammatory bowel disease?
A.
B.
C.
D.
E.

22. Zidovudine (Retrovir) is indicated for the treatment of patients with
I. hepatitis B infection
II. herpes simplex infections
III. human immunodeficiency virus (HIV) infection
A.
B.
C.
D.
E.

23. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

24. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of
A.
B.
C.
D.
E.

25. Which of the following agents have cortical stimulant action?
I. buspirone
II. pemoline
III. methamphetamine
A.
B.
C.
D.
E.

26. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

27. Potassium depletion is LEAST likely to occur in a patient using
A.
B.
C.
D.
E.

28. Pamidronate sodium (Aredia) is indicated for the treatment of
A.
B.
C.
D.
E.

29. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

30. Torsemide (Demadex) is most similar in action to
A.
B.
C.
D.
E.

31. Endorphins are
A.
B.
C.
D.
E.

32. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?
A.
B.
C.
D.
E.

33. Which of the following agents is (are) classified as antiseptics or germicides?
I. chlorhexidine gluconate (Hibiclens)
II. glutaraldehyde (Cidex)
III. benzalkonium chloride (Zephiran)
A.
B.
C.
D.
E.

34. Which of the following is a gold compound?
I. aurothioglucose (Solganal)
II. goserelin acetate (Zoladex)
III. ergonovine
A.
B.
C.
D.
E.

35. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

36. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

37. The agent most similar in pharmacological action to miglitol (Glyset) is
A.
B.
C.
D.
E.

38. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

39. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

40. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?
A.
B.
C.
D.
E.

41. Which of the following is (are) true of sal-meterol (Serevent)?
I. for the treatment of acute asthma attacks
II. available in an aerosol and inhalation powder form
III. beta 2 agonist
A.
B.
C.
D.
E.

42. Danazol (Danocrine) can best be classified as a (an)
A.
B.
C.
D.
E.

43. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug?
I. administered orally
II. stimulates erythrocyte production
III. produced by recombinant DNA technology
A.
B.
C.
D.
E.

44. Which one of the following antibiotics is a third-generation cephalosporin?
A.
B.
C.
D.
E.

45. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

46. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

47. Which of the following is true of pilocarpine (Isopto Carpine, Pilostat)?
I. similar pharmacologic action to dorzolamide (Trusopt)
II. direct-acting mydriatic
III. ingredient in Ocusert ocular therapeutic system
A.
B.
C.
D.
E.

48. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

49. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

50. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

51. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.

52. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

53. Most antipsychotic drugs can be said to have which of the following actions?
A.
B.
C.
D.
E.

54. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

55. Which of the following is (are) true of dobut amine (Dobutrex)?
I. antidepressant
II. only administered parenterally
III. beta! agonist
A.
B.
C.
D.
E.

56. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

57. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.

58. Effects expected as a result of inhaling the smoke of cannabis (marijuana) include
I. decreased pulse rate
II. perceptual changes
III. vascular congestion of the eye
A.
B.
C.
D.
E.

59. Patients who are sensitive to aspirin should avoid the use of
I. codeine
II. oxaprozin
III. ibuprofen
A.
B.
C.
D.
E.

60. Cromolyn sodium (Intal, Nasalcrom, Opticrom) is a drug that is
A.
B.
C.
D.
E.