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1. Which of the following agents is (are) classified as a leukotriene receptor antagonist?
I. ipratropium bromide
II. zileuton
III. montelukast sodium
A.
B.
C.
D.
E.

2. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

3. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

4. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.

5. Which of the following agents is (are) classified as antiseptics or germicides?
I. chlorhexidine gluconate (Hibiclens)
II. glutaraldehyde (Cidex)
III. benzalkonium chloride (Zephiran)
A.
B.
C.
D.
E.

6. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

7. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

8. Which of the following antiarrhythmic agents is (are) associated with an adverse effect known as cinchonism?
A.
B.
C.
D.
E.

9. Which of the following is (are) true of fentanyl?
I. available as a transdermal system
II. used as a local anesthetic
III. may be used as a cough suppressant
A.
B.
C.
D.
E.

10. Timentin is a product that contains ticarcillin disodium and clavulanate potassium. Clavulanate potassium
A.
B.
C.
D.
E.

11. Amrinone (Inocor) is most similar in action to
A.
B.
C.
D.
E.

12. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

13. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

14. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

15. Olsalazine sodium (Dipentum) is employed in the treatment of
A.
B.
C.
D.
E.

16. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

17. Endorphins are
A.
B.
C.
D.
E.

18. Which of the following is (are) classified as aminopenicillins?
I. bacampicillin
II. amoxicillin
III. ampicillin
A.
B.
C.
D.
E.

19. Which of the following agents is (are) indicated for the treatment of convulsive disorders
I. clonidine
II. tiagabine
III. topiramate
A.
B.
C.
D.
E.

20. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

21. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of
A.
B.
C.
D.
E.

22. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

23. Which of the following drugs may interfere with ethanol metabolism?
I. metronidazole (Flagyl)
II. chlorpropamide (Diabinese)
III. disulfiram (Antabuse)
A.
B.
C.
D.
E.

24. Which one of the following antibiotics is a third-generation cephalosporin?
A.
B.
C.
D.
E.

25. The anti-inflammatory effect of NSAIDs is due to their ability to
1. inhibit prostaglandin synthesis
II. inhibit the stimulation of the chemoreceptor trigger zone (CTZ)
III. reset the hypothalamic "setpoint"
A.
B.
C.
D.
E.

26. Which one of the following agents is most similar in action to cloxacillin?
A.
B.
C.
D.
E.

27. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

28. Which of the following is (are) true of finasteride (Proscar, Propecia)?
I. pregnancy category X
II. employed in the treatment of BPH
III. used in alopecia treatment
A.
B.
C.
D.
E.

29. In monitoring a patient receiving warfarin for the treatment of acute myocardial infarction, it is important to maintain the INR between
A.
B.
C.
D.
E.

30. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

31. Which of the following bronchodilators act by inhibiting phosphodiesterase?
I. dyphylline (Lufyllin)
II. salmeterol (Serevent)
III. nedocromil sodium (Tilade)
A.
B.
C.
D.
E.

32. Colestipol HCl (Colestid) can best be classified as a (an)
A.
B.
C.
D.
E.

33. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

34. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

35. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

36. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

37. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

38. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

39. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

40. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

41. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

42. Amrinone (Inocor) is a drug that produces
A.
B.
C.
D.
E.

43. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

44. A drug that decreases the formation of uric acid is
A.
B.
C.
D.
E.

45. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

46. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterol
A.
B.
C.
D.
E.

47. Which of the following is (are) true of milrinone lactate (Primacor)?
I. may be administered orally or parenterally
II. produces a positive inotropic action
III. produces vasodilation
A.
B.
C.
D.
E.

48. Which of the following cancer chemotherapeutic agents is (are) classified as an antimetabolite?
I. mercaptopurine (Purinethol)
II. fluorouracil (Adrucil)
III. cytarabine (Cytosar-U)
A.
B.
C.
D.
E.

49. Which of the following drugs is (are) sulfonamides?
A.
B.
C.
D.
E.

50. Which of the following calcium channel blockers may be employed parenterally in the treatment of cardiac arrhythmias?
I. verapamil (Isoptin, Calan)
II. isradipine (DynaCirc)
III. amlodipine (Norvasc)
A.
B.
C.
D.
E.

51. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

52. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

53. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

54. Phosphate binding is likely to occur when which of the following antacids are administered?
I. aluminum hydroxide
II. sodium bicarbonate
III. calcium carbonate
A.
B.
C.
D.
E.

55. Alteplase (Activase) is employed clinically as a (an)
A.
B.
C.
D.
E.

56. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

57. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

58. Torsemide (Demadex) is most similar in action to
A.
B.
C.
D.
E.

59. Danazol (Danocrine) can best be classified as a (an)
A.
B.
C.
D.
E.

60. Which of the following is a COMT inhibitor?
A.
B.
C.
D.
E.