A 57-year-old female is found unconscious
on her kitchen floor after having suffered a myocardial infarction. She has
pulmonary edema and distended jugular and peripheral veins. A midsystolic
gallop is heard upon chest auscultation. EKG shows prominent Q waves in leads
II, III, and aVF. Which of the following is most consistent with the
patient's condition?
A 10-year-old child is suspected of having pellagra because of chronic symptoms including diarrhea, a red scaly rash, and mild cerebellar ataxia. However, his diet is not deficient in protein and he appears to be ingesting adequate amounts of niacin. A sister has a similar problem. Chemical analysis of his urine demonstrates large amounts of free amino acids. Which of the following is the most likely diagnosis?
A research scientist is studying calcium fluxes in cultured cells using confocal laser scanning microscopy. The magnitude of the signal (brightness) is proportional to the strength of the calcium flux. Stimulation of which of the following receptor types would be expected to produce the strongest signal?
A pregnant southeast Asian immigrant presents for prenatal care. Her past medical history is significant for a severe illness 3 years ago characterized by fatigue, nausea, anorexia, vomiting, jaundice, joint pains, and generalized skin lesions that slowly disappeared. She has felt well recently. Which of the following laboratory tests should be ordered to investigate the patient's past illness?
A 29-year-old epileptic sanitation engineer is maintained on primidone. Ultrastructural examination of a liver biopsy reveals increased amounts of smooth endoplasmic reticulum. This change is most closely related to increases in the activity of which of the following?
Which of the following enzymes is stimulated by glucagon?
A 24-year-old woman attempts suicide by taking an overdose of diazepam. She is rushed to the emergency department, where the attending physician will most likely order which of the following treatments?
A 46-year-old woman visits her podiatrist to have several bunions removed from her right foot. She chooses conscious sedation rather than general anesthesia for this procedure. She is given intravenous midazolam to supplement the local anesthetics that are injected into her foot. Midway through the surgery, she suddenly becomes agitated, combative, and exhibits involuntary movements. The anesthesiologist determines that she is having a paradoxical reaction to the midazolam and immediately administers
A 1-year-old girl presents with a 2-day history of fever, vomiting, and watery, nonbloody diarrhea. On physical exam, she appears dehydrated. Which of the following best describes the most likely infecting organism?
A 27-year-old white male presents with a 3-week history of several swollen and painful toes and knees. He has a past history of conjunctivitis. He also describes some low back stiffness that is more severe in the morning. Which of the following is the most likely diagnosis?