Which of the following developmental abnormalities might account for unexplained small intestinal bleeding?
A 25-year-old woman with sickle cell anemia complains of steady pain in her right upper quadrant with radiation to the right shoulder, especially after large or fatty meals. Her physician diagnoses gallstones. Of which of the following compounds are these stones most likely composed?
A 32-year-old, blood type A positive male receives a kidney transplant from a blood type B positive female donor with whom he had a 6-antigen HLA match. Once the kidney is anastomosed to the man's vasculature, the transplant team immediately begins to observe swelling and interstitial hemorrhage. After the surgery, the patient developed fever and leukocytosis and produced no urine. Which of the following is the most likely explanation?
A 32-year-old pregnant woman is told by her physician to avoid taking aspirin. Use of aspirin is contraindicated, especially during the last part of pregnancy, because aspirin affects which of the following hematologic parameters?
Routine physical examination of a 55-year-old man demonstrates marked finger clubbing. Radiography of the hand shows new bone formation beneath the periosteum. With which of the following disorders is this finding most strongly associated?
An elderly woman with a history of multiple oral ulcers presents with flaccid bullae on her scalp, face, and trunk. Manual pressure on the skin produces separation of the upper layer of the epidermis, followed by eventual sloughing of the skin. The patient has been in relatively good health until recently, and denies taking any medications. A biopsy of one of the skin lesions reveals separation of epithelial cells above the basal layer. Autoantibodies to which of the following components would most likely be found in this patient?
A patient develops an acute febrile illness with shivers, nonproductive cough, and pleuritic chest pain. Five days later, he presents to the emergency room after abruptly having 'coughed up' nearly a cup of blood-stained sputum. Which of the following is most likely to be seen on chest x-ray?
A 2-year-old child presents to the pediatrician with hematuria. Examination reveals hypertension and an abdominal mass. A tumor is localized to the right kidney and biopsy reveals a stroma containing smooth and striated muscle, bone, cartilage, and fat, with areas of necrosis. The gene for this disorder has been localized to which of the following chromosomes?
In a genotypic male, the testes fail to develop, and do not secrete testosterone or MÃ¼llerian regression factor. Which of the following best describes the in utero reproductive system development of this individual?
A newborn boy does not pass meconium until 48 hours after his birth . Two weeks later his mother reports that he has not been passing stool regularly. Anorectal manometry reveals increased internal anal sphincter pressure on rectal distention with a balloon. Radiographic studies revea l massive dilation of the colon proximal to the rectum. This indicates a developmental abnormality in which of the following embryonic tissues?