A 55-year-old man had been in good health since receiving a heart transplant for severe atherosclerotic disease. Five years after transplantation, the patient died suddenly, without any premonitory symptoms, while working in his garden. He had been maintained on cyclosporin since his transplant. Which of the following complications would most likely be found at autopsy in the transplanted heart?
An elderly lady is brought to the emergency room after drinking insecticide that she thought was tea. After her stomach is pumped, her sense of smell is tested and it is found that she can not distinguish common smells (e.g., an orange, coffee). CT scan of the head demonstrates a mass in the olfactory groove area. The axons likely compressed by this mass project to which of the following structures?
A 27-year-old man develops bilateral parotid gland swelling and orchitis, and is generally ill with fever of 102° F. Which of the following substances is most likely to be significantly elevated in the patient's serum?
A 55-year-old man presents to the emergency room with crushing substernal pain and left shoulder pain of 2 hours duration. The pain is not relieved by sublingual nitroglycerin, and the electrocardiogram shows ST elevation in several leads. Aspirin and streptokinase therapy are initiated, and the patient is admitted to the intensive care unit. The next morning, serum cardiac enzymes are elevated to 4 times the upper limit of normal, and the electrocardiographic changes are still present. Which of the following is the most likely diagnosis?
Which of the following amino acids is post-translationally hydroxylated in the cytoplasm of fibroblasts?
Microscopic examination of a cancer cell reveals a cell in an abnormal telophase in which three clusters of chromosomes are seen. An abnormality of which of the following would be most likely to produce this alteration?
A 58-year-old man with fainting spells and exercise intolerance is found to have a bicuspid aortic valve with marked aortic stenosis. Which of the following physical findings would be prominent in this patient?
A 48-year-old man complaining of chest pain is brought to the emergency room. Physical examination followed by echocardiography demonstrates aortic stenosis. His coronary blood flow is increased. Which of the following is the most likely explanation for the increased coronary blood flow in this individual?
A 45-year-old man presents to the emergency department with severe headache and vomiting. A CT scan shows a well-circumscribed cystic lesion within the 3rd ventricle; there is no calcium deposition. The cyst is surgically removed. On histologic examination, the wall of the cyst consists of a single layer of mucin-producing columnar epithelium with a ciliated apical surface. Which of the following is the most likely diagnosis?
A 36-year-old female is brought to the emergency room by her husband who says that she 'complained of a severe headache then lost consciousness.' She has a history of hypertension and had been on several different medications. The examining physician notes that she is unable to move her arms and legs, but can blink her eyes. When the physician asks her to blink twice if she can hear him, she promptly does so. In which of the following structures is this woman's lesion most likely located?